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Why I've Changed My Mind on Benzoyl Peroxide: A Professional Insight

For years, I was strongly against the use of Benzoyl Peroxide (BPO) in treating acne. However, after treating acne for over 17 years and witnessing countless cases, I've come to recognize the significant benefits BPO can offer in managing acne effectively. Here’s why BPO has earned a spot in my recommended acne treatment protocol:


1. Potent Antibacterial Properties

BPO is highly effective at targeting and eliminating Cutibacterium acnes (formerly known as Propionibacterium acnes), the bacteria responsible for inflamed acne. By killing this bacteria, BPO helps reduce active breakouts and prevents new ones from forming.


2. Anti-Inflammatory Effects

Beyond its antibacterial properties, BPO has shown to have anti-inflammatory benefits. Reducing inflammation is key to calming red, swollen acne lesions, which speeds up healing and minimizes post-inflammatory hyperpigmentation.


3. Non-Antibiotic Option with No Risk of Resistance

Unlike antibiotics, BPO does not lead to bacterial resistance. As antibiotic resistance becomes an increasing concern in dermatology, BPO stands out as a powerful alternative that remains effective over time.


4. Promotes Skin Cell Turnover

BPO encourages the shedding of dead skin cells, helping to unclog pores. By keeping the skin’s surface clear, it reduces the formation of new comedones (blackheads and whiteheads) and prevents pores from becoming clogged, a common precursor to breakouts.


5. Effective for All Stages of Acne

BPO is versatile enough to be used in different formulations and concentrations, making it suitable for treating mild to moderate acne as well as being an adjunctive therapy for more severe cases.


6. Works Well in Combination Therapies

BPO enhances the effectiveness of other acne treatments when used together. For instance, pairing BPO with retinoids or topical antibiotics can maximize results, offering comprehensive care by targeting multiple factors that contribute to acne.


7. Improved Formulations for Better Tolerability

Modern advancements in formulation have made BPO much more tolerable for all skin types. Lower concentrations (e.g., 2.5% instead of the traditional 10%) are now widely available and still provide significant benefits with less risk of irritation or dryness.





My stance on BPO has evolved due to the undeniable results I’ve seen in clinical practice. Incorporating it into a skincare regimen can play a pivotal role in achieving clearer skin while being mindful of long-term skin health. As always, the key is finding the right formulation and frequency to suit each individual’s skin type and needs.


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